Endocrine Abstracts

Introduction: Osteoporosis is a major health problem in our countries. Primary hyperparathyroidism and obesity surgery increase this risk of adverse events such as fractures. We report the case of a patient with mild asymptomatic hyperparathyroidism with low serum mild hypercalcemia non-osteoporotic who developed osteoporosis after obesity surgery improved by parathyroidectomy.Case: This is a female 55-year-old patient with past history appendectomy, str...

Introduction: Postoperative upper digestive endoscopy seems to give conflicting results in literature after obesity surgery. Some stressed on the frequency of major digestive lesions such as esophagitis, cancer or endo brachy esophagus (EBO) especially after Sleeve Gastrectomy (SG). The incidence of EBO after SG was found in 1.2% to 15% at ten years of follow up. Accordingly to European Guidelines, it is mandatory to perform a routinely preoperative gastroscopy but not after s...

This study assessed the dietary and medical knowledge before and after a group workshop viewing a 5-min animation film in patients with gestational diabetes (GD) (https://www.youtube.com/watch?v=Maf-Uos9oLQ). This animation movie (without speech) explains the course of the patients suffering from GD by emphasizing the stakes, the diet and the medical measures.Patients and methods: This is a prospective self-assessment study of 10 questions in 100 consecu...

Metformin Associated Lactic Acidosis (MALA) is defined by a Ph <7.35 and lactate levels greater than 5 mM. It must be distinguished from other lactic acidosis usually secondary to septic shock. Renal functional prognosis and mortality are not clearly separated in publications and many make the amalgam between the two entities with an estimated mortality of 30 to 50% and poor renal prognosis.We did a retrospective, observational, cohort study of patie...

Many studies but not all showed an increase in employment after bariatric surgery by 17–29%. We analyzed the relation of this increase of employment rate with weight loss, satisfaction and deprivation score. In an observational study, we evaluated the rate of employment (mean±S.E.) 2.3 years ±0.1 after bariatric surgery. We mailed to 791 patients a simple self-questionnaire to assess the employment status deprivation, satisfaction scale and Barros...

We know that non-severe hypoglycaemia (SH) should be treated with the immediate intake of 15–20 g of oral glucose, there are no data according to our knowledge in the current literature for the dose of glucose that is necessary to inject in SH. We have analysed retrospectively the treatment of pre hospital SHs as reported after an emergency call for intervention. Our primary objective was to know the dose of the given glucose and our secondary objective was to know the fa...

We analyzed the eating behavior and physical activity in patients operated in our obesity surgery center and their relation to weight loss. We mailed to patients a simple self-questionnaire to assess the use of eating or physical activity advices given from our stuff during the preoperative period. Patients had a bariatric surgery from September 1, 2013 to August 2016 Questionnaires were collected during their follow-up (September 2017). One hundred forty four out of 750 patie...

Since its first description in 2000, Longitudinal Gastrectomy (LG) has become the first surgical procedure in the treatment of morbid obesity in the world, exceeding in numbers Gastric Bypass (GB). GB is considered to have better results regarding long-term weight loss and improvement in co-morbidities. We aimed to demonstrate that LG is non inferior to GB for a composite end point that included more than 50% excess weight loss from the baseline and surgery related complicatio...

Normosmic congenital hypogonadotropic hypogonadism (nCHH) is a rare reproductive disease leading to lack of puberty and infertility. Loss-of-function mutations of GNRH1 gene are a very rare cause of autosomal recessive nCHH. R31C GNRH1 is the only missense mutation that affects the conserved GnRH decapeptide sequence. This mutation was identified in a CpG islet in nine nCHH subjects from four unrelated families, giving evidence for a putative ‘hot spot&#...